What is Pioglitazone?
Pioglitazone is a prescription drug taken to improve glycemic control. This drug belongs to a new class of Type 2 diabetes medications called thiazolidinedione. These drugs modulate the expression of genes involved in glucose and lipid metabolism through the activation of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ). This results in a reduction in insulin resistance in the liver, muscle and adipose tissue.
Pioglitazone is available in tablets of 15 mg, 30 mg, and 45 mg. This medication comes with 100 30-mg tablets and a product insert. It is taken orally once daily.
What is it used for?
Pioglitazone, marketed as Actos, is meant for the treatment of Type 2 diabetes. As this treatment depends on the presence of native insulin, it is not used for Type 1 diabetes treatment. This medication should be considered only in patients for whom diet, exercise, and first-line diabetic medications like metformin have not provided adequate glycemic control.
Why use Pioglitazone?
This antidiabetic medication has a unique mechanism of action and is suitable to be used as a complement to most other types of medications, including sulphylureas and metformin. This drug has been shown to lessen the risk of developing cardiovascular disease, a major concern in diabetic patients.Click to read more Click to read less
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