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What is Jardiance (Empagliflozin)?

Jardiance is an oral diabetes medicine that can help you regulate your blood sugar levels better. Its chemical, or generic version is Empagliflozin, and it belongs to the larger gliflozin family of antidiabetic medications. Along with the other members of the gliflozin family, it works by helping your kidneys get rid of excess glucose from your bloodstream.

What is it used for?

Jardiance is used along with a healthy diet and regular exercise to help improve and regulate blood sugar level control in adults with type 2 diabetes mellitus.

How does Empagliflozin work?

Empagliflozin (Jardiance), like other members of the gliflozin family of antidiabetic drugs, works to lower blood sugar levels by increasing the amount of sugar that is eliminated from the body through your urine. These drugs are designed to block your kidney’s ability to re-absorb sugar from your blood. When this re-absorption is prevented in your kidneys, your blood sugar levels will drop as glucose begins to be eliminated through your urine. Also, it increases your overall rate of urination, so even more blood sugar is eliminated from your body, causing your blood sugar levels to stabilize.

How to take this medication

Always remember to follow the directions given to you by your doctor. Jardiance is recommended to be taken once a day, at any time of the day, by mouth, and with or without food. Swallow the tablets whole, and do not cut or divide the tablets up.

Jardiance Dosage

The usual, recommended adult starting dose of Jardiance is one 10 mg tablet a day. Your doctor may increase your dose to one 25 mg tablet per day if you need to further control your blood sugar level.

Missed Doses

Never take a double dose. If it is 12 hours or more until it is time for your next dose, take it as soon as you remember. Then take your next dose at the normal time. If it is fewer than 12 hours until your next dose, skip the missed dose, and then take your next dose at the normal time.

Warnings and Precautions

Do not take the drug if you:

  • are allergic to empagliflozin, or any of the other ingredients
  • have type 1 diabetes (a diabetic condition in which your body does not produce any insulin)
  • have diabetic ketoacidosis (DKA, a complication of diabetes) or a history of DKA
  • have a severe kidney condition or you are on dialysis
  • have severe liver disease
  • are pregnant or are planning on becoming pregnant. Talk with your doctor about the best options to control your blood sugar levels while you are pregnant.
  • are currently breastfeeding or are planning to breastfeed, as it is not known if it can pass into your breast milk.

Jardiance is not recommended for use in patients under 18 years of age. It will cause your urine to test positive for sugar (glucose). It may cause changes in your cholesterol or fat levels in your blood.

It may also cause abnormal kidney function. Your doctor will do blood tests to monitor how well you are tolerating the drug and how well your kidneys are working. Jardiance also increases the chance of getting a yeast infection of the penis or vagina. This is more likely in people who have had yeast infections in the past. It may also cause lightheadedness or dizziness. Do not drive or operate machines until you are confident you know how the medicine affects you personally.

Side effects

In addition to its therapeutic effects, some unwanted effects may be caused by Jardiance. In the event that any of these side effects occur to you, they may require medical attention. Make sure to let your doctor know if these, or any other side effects persist.

Common negative effects may include:

  • urinary tract infection
  • yeast infection of the penis or vagina
  • dehydration
  • unusual thirstiness
  • passing more urine than normal, or needing to pass more often
  • itching
  • rash
  • straining or pain when emptying the bladder

Uncommon negative effects may include:

  • cervicitis (an inflammation of the cervix, particularly the lower, narrow end of your uterus that opens into the vagina)
  • genital candidiasis (genital itching, burning, and sometimes accompanied with discharge)
  • vaginal infection
  • vulvitis (inflammation of the vulva, that can include the labia majora, labia minora, clitoris, and introitus)
  • anxiety
  • blurred vision
  • fast heartbeat
  • cold sweats
  • chills
  • confusion
  • increased hunger
  • dizziness, feeling faint, or lightheadedness
  • decreased urination
  • rapid breathing
  • headache
  • slurred speech
  • nausea
  • nightmares
  • unusual tiredness or weakness
  • seizures
  • shakiness
  • sweating

Talk to your health care provider about any side effect that bothers you or does not go away. These are not all the possible negative effects. Call your doctor for medical advice about side effects.

Manufacturer: Boehringer Ingelheim

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