What is Januvia 100mg?
Januvia is a prescription-only medication containing sitagliptin, which is a dipeptidyl peptidase-4 inhibitor. It is taken orally to reduce blood sugar levels. Januvia is supplied in a package containing 30 tablets.
What is it used for?
Januvia is used to lower blood sugar levels in patients with type 2 diabetes mellitus. It is meant to be used with adequate diet and exercise for better results. Januvia can be used with other anti-diabetic medications, such as insulin, but the doses might need to be reduced to avoid episodes of hypoglycemia.
Why use this medication?
Januvia is capable of reducing HbA1C levels by about 0.8%, as shown in a study investigating its efficacy. When used with metformin, however, HbA1C levels dropped by 1.6 to 2.1%. In addition to that, Januvia is also found be suitable and effective when used as a monotherapy in elderly patients. A 24-week study found that Januvia reduced HbA1C levels by as much as 0.5% compared to 0.2% of the placebo group when used in patients aged 65 years and above.
Januvia has also been compared to common sulfonylurea drugs, such as glipizide and glimepiride. Studies have found that there is strong HbA1C lowering effects, similar to the sulfonylureas, but with a lower chance of hypoglycemia and minimal risk of weight gain. This improved safety profile is particularly advantageous in elderly patients, since they are more susceptible to hypoglycemia, and in obese patients.Click to read more Click to read less
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