What is Janumet XR 50mg/1,000mg?
Janumet XR is a combination drug used in the treatment of diabetes mellitus. The drug consists of two types of diabetic medicines (including extended-release metformin hydrochloride and immediate-release sitagliptin), which have distinctively different mechanisms of action. Acting as a biguanide, metformin hydrochloride (HCl) lowers postprandial and basal plasma glucose by improving insulin sensitivity and decreasing hepatic glucose production. On the other hand, sitagliptin has inhibitory actions on dipeptidyl peptidase-4 (DPP-4) receptors. Janumet XR is available in film coated tablets of 50mg/1000mg sitagliptin and metformin hydrochloride, respectively. Alternatively, it comes in the concentrations of 50mg/500mg and 100mg/1000mg.
What is it used for?
Janumet XR is commonly used to improve glycemic control in diabetic patients. In order to achieve optimal blood glucose control, Janumet XR should be used adjunctively with non-pharmacological treatments such as dietary modification or exercise. Janumet XR is only intended for the treatment of type 2 diabetes (it is generally ineffective in treating type 1 diabetes or diabetic ketoacidosis). This antihyperglycemic drug should only be used in adults over 18 years old. Its efficacy and safety are not well studied in pediatric patients.
Why use it?
The FDA-approved Janumet XR effectively improves blood glucose control in patients who suffer from type 2 diabetes. For better results, follow the doctor’s instructions closely (including any lifestyle recommendations such as exercise and diet).Click to read more Click to read less
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