What is Lucentis (Ranibizumab)?
Lucentis is an intraocular medication containing the active ingredient ranibizumab used to treat various degenerating eye conditions that cause vision loss. Ranibizumab is an antibody fragment that selectively binds to the human vascular endothelial growth factor A (VEGF-A) protein. This form of Lucentis is a sterile clear colorless to pale solution for injection, and comes in a clear, colorless glass vial. It is administered as an injection into the eye. The recommended dose is 0.5mg, given every 1–3 months, according to the therapeutic indication.
What is Lucentis used for?
Lucentis prevents further growth and leakage of newly formed blood vessels in the eye, which are contributing factors to retinal damage seen in eye diseases like wet age-related macular degeneration (AMD), diabetic macular edema (DME), choroidal neovascularization (CNV) secondary to pathologic myopia (PM), and CNV due to other causes. Lucentis binds to and inhibits the activity of VEGF-A, a retinal protein involved in endothelial cell proliferation and neovascularization.
Why use it?
Lucentis has been proven to slow the progression of vision loss, improve vision, and, thus, restore the ability to perform visual activities, like driving and reading. Anti-VEGF drugs like Lucentis are very effective treatments for wet AMD and represent first-line therapies for these types of eye diseases.Click to read more Click to read less
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