What is Metformin Hydrochloride?
Metformin is an oral antidiabetic medication under the drug class oral biguanide that is commonly used to improve blood sugar level control in both adults and children with Type 2 diabetes mellitus (T2DM). It is supplied in bottles of 100, 360, or 500 in tablets. The cost per tablet reduces as more are bought at the same time.
What is Metformin Hydrochloride used for?
Metformin is mainly used for patients with T2DM, and also for patients with polycystic ovarian syndrome (PCOS). The mechanism of action of metformin is unique and different from other antidiabetic medications but also complements well with these other antidiabetic therapies. Since metformin works by decreasing liver production of sugar, intestinal sugar absorption, and by increasing insulin sensitivity, it can be used with other medications that increases insulin secretion such as sulfonylureas.
Why use this medication?
Metformin has been consistently recommended as the starting treatment for T2DM. A joint consensus algorithm developed by the American Diabetes Association and the European Association for the Study of Diabetes suggest a combination of metformin and lifestyle changes is one of the most efficient, safe, and cost saving measure. Furthermore, in a pivotal study, researchers found that metformin therapy reduced the risk of heart attack by as much as 33%. For PCOS, metformin can significantly improve the quality of life of the patients as it lowers their androgen hormones, restores normal menstrual cycle and ovulation, and improves pregnancy rates.
An important distinction to make regarding metformin is that the medication improves insulin resistance which is the bane of many obese diabetic patients. Furthermore, metformin has a very low risk of hypoglycemia compared to other medications.Click to read more Click to read less
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