What is Glyburide 2.5mg?
Glyburide 2.5mg is an oral antidiabetic drug (OAD) that is used as an adjunctive therapy alongside diet modification and exercise to treat patients diagnosed with type 2 diabetes mellitus. Glyburide is classified as a sulfonylurea, which functions by simulating the β cells of the pancreas to release both basal insulin secretion and meal-stimulated insulin. This class of OAD also works by increasing the number and sensitivity of insulin receptors; increasing peripheral glucose utilization; and decreasing glucose production in the liver.
What is it used for?
Patients are prescribed with this medication when lifestyle modifications alone are ineffective. Glyburide 2.5mg is administered orally with the first main meal of the day to reduce the risk of hypoglycemia. The starting dosage is usually 2.5 to 5mg once daily. The dose may be gradually increased by 2.5mg until the desired treatment response is obtained. The maintenance dosage is between 1.25 to 20mg orally once daily, as single or divided doses. The maximum dose is 20mg of Glyburide once daily. Patients who are hypersensitive to other OADs may be prescribed a lower initial dose of 1.25mg.
Why use this medication?
Consistent Glyburide intake, in combination with diet control and adequate exercise, will help to reduce elevated blood sugar level.
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