PPE NOW AVAILABLE - CLICK HERE TO SHOP
Contact us
Customer Service Hours
Mon-Fri 9AM to 6:00PM EST
Email service@canadianinsulin.com
Phone 1-844-560-7790
Fax 1-866-951-0118

Non-Insulin Injectable Diabetes Medications

Non-Insulin Injectable Diabetes Medications

Why Use Non-Insulin Medications for Diabetes?

While many people assume that insulin is the best—or only—medication to treat diabetes, that is not the case. Many people with Type 2 diabetes can manage their condition with non-insulin medications alongside a diabetes-focused diet and exercise. In fact, many doctors may prescribe non-insulin medications before resorting to insulin. There are many reasons for such a decision, including:

  • Blood sugar levels
  • Patient’s treatment and medical history
  • Weight
  • Age
  • Other health issues

The following are the most commonly prescribed non-insulin injectable medications for diabetes:

Exenatide (Byetta)

Exenatide, sold as the brand name Byetta, increases insulin levels while eating by keeping food in the stomach longer. It also helps with weight loss and lowers the levels of glucose released by the liver. It should be taken an hour before a meal, twice a day. The side effects of exenatide include:

  • Nausea
  • Vomiting
  • Decrease in appetite

Exenatide Extended Release (Bydureon)

The extended release version of exenatide, sold as the brand name Bydureon, is injected once per week. It provides the same effects as Byetta and cannot be used in combination with it. It can be taken in combination with metformin, sulfonylurea, or thiazolidienediones.

Liraglutide (Victoza)

Victoza, the brand name of liraglutide, lowers glucose levels released by the liver and increases insulin levels when you eat. Additionally, it helps keep food in the stomach for a longer period, which can lead to decreased appetite and weight loss. It is taken once daily at any time and does not need to be taken with food. It can be used with sulfonylureas, metformin, or thiazalidinediones.

The side effects include:

  • Headache
  • Diarrhea
  • Decreased appetite
  • Nausea

Dulaglutide (Trulicity)

Dulaglutide, sold as the brand name Trulicity, is another non-insulin diabetes medication that works by keeping food in the stomach longer. This helps to increase insulin levels during meals and decrease the amount of glucose released. It should not be taken if the patient has a history of medullary thyroid carcinoma (MTC) or by patients with Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2).

The side effects include:

  • Decrease in appetite
  • Nausea
  • Vomiting
  • Diarrhea

Albiglutide (Tanzeum)

Albiglutide, which is sold under the brand name Tanzeum, comes as a powder and a liquid that must be mixed together. It should not be administered to patients with a medical or family history of MTC or MEN 2. It keeps food in the stomach longer, increasing insulin when eating, and lowering levels of glucose secreted by the liver.

The side effects include:

  • Nausea
  • Diarrhea

Pramlintide (Symlin)

Symlin, which is the brand name of pramlintide, is a synthetic preparation of amylin. Amylin is released at the same time as insulin while eating. It helps a person feel fuller by keeping the stomach full longer. It also decreases the amount of glucose released by the liver. It is suitable for patients with both Type 1 and Type 2 diabetes and is given before meals. It is typically injected at the same time as insulin, though the two medications must be injected separately. Pramlintide also helps with weight loss.

The side effects include:

  • Decreased appetite
  • Vomiting
  • Nausea

---

Disclaimer: Please note that the contents of this community article are strictly for informational purposes and should not be considered as medical advice. This article, and other community articles, are not written or reviewed for medical validity by Canadian Insulin or its staff. All views and opinions expressed by the contributing authors are not endorsed by Canadian Insulin. Always consult a medical professional for medical advice, diagnosis, and treatment.
Reset Your Password

Please enter your Username below and we will send a new password to the email associated with your account. Check your spam folder if you do not receive your new password.

Still having trouble logging in?

If you’re unable to log in, please call our customer service at 1-844-560-7790.