What is Canagliflozin?: Side Effects and Dosing
What is Canagliflozin?
It is an oral prescription drug that is used to improve glycemic control in type 2 diabetic patients. Canagliflozin is also known as Invokana. This oral diabetes drug is usually prescribed together with a proper diet and exercise program to control high level of blood sugar. Controlling the high level of blood glucose is important because it can prevent the risk of developing problems such as loss of the limbs, kidney damage, and blindness. Invokana belongs to a class of medication known as sodium glucose co-transporter 2 or SGLT-2 inhibitor. SGLT-2 inhibitor drugs work by increasing the amount of glucose that is excreted via urine. As such, it helps to lower high levels of blood glucose in the body. Invokana can also be taken as a combination therapy with other oral diabetes drugs such as metformin. Before you start taking canagliflozin, it is advisable you inform your doctor of other medications you are using. This is because Invokana is known to interact with other drugs like insulin and blood pressure drugs.
The drug dosing
The dosage of canagliflozin varies depending on your age, severity of your condition, and how you respond to the first dose. The medication is available in dose strength of 100mg and 300mg. Typically, your doctor may start you at a dose of 100mg that should be taken once every day. In case your blood sugar level is not adequately managed with the initial dose, your doctor may increase your dosage to 300mg. This dose should be taken once every day before breakfast.
Canagliflozin side effects
Taking canagliflozin to control your level of blood sugar can lead to side effects. Usually, you may experience mild side effects when you start taking Invokana. The side effects may go away after you get used to Invokana. In case the side effects are more severe, you will need to see a doctor.
The following are some of the common side effects
- Men may have yeast infection of the penis, with symptoms like swelling, pain, discharge, and rash
- Women may have vaginal yeast infection, with symptoms such as itching and vaginal discharge
- Urinary tract infection with symptoms such as frequent urination, cloudy urine, and the sensation of burning while urinating
Diabetic patients who take canagliflozin do not always experience serious side effects. In case you have serious side effects, you should stop using Invokana and contact your health-care provider right away. If you think your symptoms are putting your life at risk, visit the nearest hospital for emergency help.
The following are serious side effects
- Hypoglycemia with symptoms like nervousness, shakiness, hunger, nausea, blurred vision, sweating, weakness, and headache
- Kidney problems with symptoms such as difficulty urinating and blood in the urine
- Dehydration that has symptoms like dizziness, lightheadedness, and fainting
- High blood potassium
- Allergic reaction symptoms such as hives, rash, difficulty breathing, swelling of tongue, face and lip
Disclaimer: Please note that the contents of this community article are strictly for informational purposes and should not be considered as medical advice. This article, and other community articles, are not written or reviewed for medical validity by Canadian Insulin or its staff. All views and opinions expressed by the contributing authors are not endorsed by Canadian Insulin. Always consult a medical professional for medical advice, diagnosis, and treatment.